Brief Introduction

Synonyms--- Fenugreek; Trigonella foenum-graecum), Hu Lu Ba, "Greek hay", Methi

4 - hydroxyisoleucine

Chemical Name:
CAS NO.: 55399-93-4

Molecular Formula: C6H13NO3

Mol. Wt.: 147

Molecular Structure:

4 - hydroxy-isoleucine (4-hydroxyisoleucine) is present in fenugreek plant in a non-protein amino acids, mainly in fenugreek seeds, promote the role of insulin secretion, in addition, 4 - hydroxy-isoleucine will be more efficient to creatine in the muscle cells to enhance muscle strength and lean muscle mass, increase strength and size of muscle cells.

Furostanol Saponins (Protodioscin)

Chemical Name: 26-o-beta-d-glycopyranosyl-22-hydroxyfurost-5-ene-3beta, 26-diol-3-o-beta-diglucorhamnoside
CAS NO.: 55056-80-9

Molecular Formula: C51H84O22

Mol. Wt.: 1049.2

Molecular Structure:

Furostanol saponins exist in the genus fenugreek saponin, by increasing the body produce luteinizing hormone dehydroepiandrosterone and to increase testosterone levels. It has been used to treat sexual dysfunction, also used to stimulate muscle growth. Both effects are due to its increase in testosterone levels. The present study indicates that its main components - Furan steroid saponin (formerly diosgenin saponin) play a decisive role in the active ingredient.

Fenugreek; Trigonella foenum-graecum), the name from Latin for "Greek hay", is a plant in the family Fabaceae. Fenugreek is used both as a herb (the leaves) and as a spice (the seed, often called methi). The plant is cultivated worldwide as a semi-arid crop and is a common ingredient in many curries.

The cuboid yellow to amber coloured fenugreek seeds are frequently used in the preparation of pickles, curry powders, and pastes, and the spice is often encountered in the cuisine of the Indian subcontinent. The dried leaves - also called kasuri methi (or kasoori methi in India)- have a bitter taste and a characteristically strong smell.

Fenugreek seeds are a rich source of the polysaccharide galactomannan. They are also a source of saponins such as diosgenin, yamogenin, gitogenin, tigogenin, and neotigogens. Other bioactive constituents of fenugreek include mucilage, volatile oils, and alkaloids such as choline and trigonelline.

Fenugreek seeds are used as a medicinal in Traditional Chinese Medicine under the name Hu Lu Ba, where they are considered to warm and tonify kidneys, disperse cold and alleviate pain. Main indications are hernia, pain in the groin. They are used raw or toasted. In India about 2-3g of raw fenugreek seeds (called Methi in India) are swallowed raw early in the morning with warm water, before brushing the teeth and before drinking tea or coffee, where they are supposed to have a therapeutic and healing effect on joint pains, without any side effects.

Fenugreek seed is widely used as a galactagogue (milk producing agent) by nursing mothers to increase inadequate breast milk supply. Studies have shown that fenugreek is a potent stimulator of breast milk production and its use was associated with increases in milk production of as much as 900%. It can be found in capsule form in many health food stores.

Several human intervention trials demonstrated that the antidiabetic effects of fenugreek seeds ameliorate most metabolic symptoms associated with type-1 and type-2 diabetes in both humans and relevant animal models by reducing serum glucose and improving glucose tolerance. Fenugreek is currently available commercially in encapsulated forms and is being prescribed as dietary supplements for the control of hypercholesterolemia and diabetes by practitioners of complementary and alternative medicine. Fenugreek contains high dietary fiber, so a few seeds taken with warm water before going to sleep helps avoiding constipation.

The Fenugreek Seed Extract used in dietary supplements is derived from the seeds of the plant Fenugreek (Trigonella foenum-graecum L.).

Benefits

• Anti-diabetes: To promote the role of insulin secretion

• Lowering cholesterol

• To stimulate and improve sexual performance by enhancing the level of hormones.

• To enhance muscle building: improve muscle strength and lean muscle mass

•. Galactagogue Effects

Mechanism

As above-mentioned.

Safety

Fenugreek Seed Extract is safe, no side effects have been reported to date, but relying on this type of treatment alone, and avoiding conventional medical care, may have serious health consequences.

Dosage

•  The typical dose is 300-900mg per day (usually in 2-3 doses throughout the day).
•  Consult physicians for different condition specifics.

GNI’s  Features and Benefits:

Fenugreek Seed Extract is one of GNI's most competitive products, with many advantages as list in the following, produced as our patent-pending process and know-how technology from Trigonella foenum-graecum L. seeds.

•  Produced with pure water only

•  High purity: over 95%

•  NO solvent - residual free

•  Pesticide-free

•  Crystal white an Dark Yellow in appearance

•  High solubility in water

•  High anti-bacteria, and longer shelf life

Product Specifications:

4-Hydroxyisoleucine 5%, 60%, 95% HPLC (Hydroxyl-ILE)

Furostanol saponins 50% UV