Brief Introduction

Synonyms--- Roseroot, Skye flora, Golden Root, Aaron’s Rod, hóng jǐng tiān (Chinese:红景天).

Rosavin

Chemical Name: (2E)-3-phenylprop-2-en-1-yl 6-O-α-L-arabinopyranosyl-α- D-glucopyranoside
Molecular Formula: C₂₀H₂₈O₁₀

Mol. Wt.: 428.430

Molecular Structure:

Rosavinis a glycoside compound found in the plant Rhodiola rosea. It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with salidroside.

Salidroside(Rhodioloside)

Chemical Name:2-(4-hydroxyphenyl)ethyl β-D-glucopyranoside
Molecular Formula:C₁₄H₂₀O₇

Mol. Wt.: 300.304

Molecular Structure:

Salidroside(Rhodioloside) is a glycoside compound found in the plant Rhodiola rosea. It is thought to be one of the compounds responsible for the antidepressant and anxiolytic actions of this plant, along with rosavin. Salidroside may be more active than rosavin, even though many commercially marketed Rhodiola rosea extracts are standardised for rosavin content rather than salidroside.

Rhodiola roseais a plant in the Crassulaceae family that grows in cold regions of the world. These include much of the Arctic, the mountains of Central Asia, the Rocky Mountains, and mountainous parts of Europe, such as the Alps, Pyrenees, Carpathian Mountains,Scandinavia, Iceland, Great Britain and Ireland. The perennial plant grows in areas up to 2280 meters elevation. Several shoots grow from the same thick root. Shoots reaches 5 to 35 cm in height. Rhodiola rosea is dioecious - having separate female and male plants.

Rhodiola roseacontains a variety of compounds that may contribute to its effects, including the class of rosavins which include rosavin, rosarin, and rosin. Several studies have suggested that the most active components are likely to be salidroside (rhodioloside) and tyrosol, with other components being inactive when administered alone, but showing synergistic effects when a fixed combination of rhodioloside, rosavin, rosarin and rosin was used. Rosavin, rosarin, rosin and salidroside (and sometimes p-tyrosol, rhodioniside, rhodiolin and rosiridin) are among active ingredients of Rhodiola rosea, these compounds are mostly polyphenols. Although these phytochemicals are typically mentioned as specific to Rhodiola extracts, there are many other constituent phenolic antioxidants, including proanthocyanidins, quercetin, gallic acid, chlorogenic acid and kaempferol.

Rhodiola roseamay be beneficial to increase energy and mental performance for people suffering from Hashimoto's disease, and be effective for improving mood and alleviating depression. Pilot studies on human subjects showed that it improves physical and mental performance, and may reduce fatigue.

The Rhodiola rosea Extract used in dietary supplements is derived from the roots of Rhodiola rosea L..

Benefits

•  Antidepressant

•  Reduce fatigue and increase energy

•  Mental support

Mechanism

Rhodiola rosea's effects potentially are related to optimizing serotonin and dopamine levels due to monoamine oxidase inhibition and its influence on opioid peptides such as beta-endorphins, although these specific neurochemical mechanisms have not been clearly documented with scientific studies.

Rhodiola is included among a class of plant derivatives called adaptogens which differ from chemical stimulants, such as nicotine, and do not have the same physiological effects.

In Russia and Scandinavia, Rhodiola rosea has been used for centuries to cope with the cold Siberian climate and stressful life. Such effects were provided with evidence in laboratory models of stress using the nematode C. elegans, and in rats in which Rhodiola effectively prevented stress-induced changes in appetite, physical activity, weight gain and the estrus cycle.

Safety

Rhodiola rosea Extract is safe, no side effects have been found.

Dosage

•  The typical dose is 200-700mg per day (usually in 2-3 doses throughout the day).
•  Consult physicians for different condition specifics.

Rhodiola roseaextract is mainly used in the form of capsules or a tablet, though tinctures are also available. The capsules and tablets often contain 100 mg of a standardized amount of 3 percent rosavins and 0.8–1 percent salidroside because the naturally occurring ratio of these compounds in Rhodiola rosea root is approximately 3:1, and of course, they contain many other suspected active biochemical compounds in the plant (12 Kinds or 28 Kinds are only two declarations by some companies in this line).

A typical dosage is one or two capsules or tablets daily; one in the morning and when taking two, one in the early afternoon. Rhodiola rosea should be taken early in the day because for some it can interfere with sleep. Others can take it in the evening with no effect on sleep patterns. If a user becomes overly activated, jittery or agitated then a smaller dose with very gradual increases may be needed. It is contraindicated in excited states.

The dose may be increased to 200 mg three times a day if needed. A high dose is considered to be daily intakes of 1,000 mg and above.

While animal tests have suggested a variety of beneficial effects for Rhodiola rosea extracts, only for depression is there scientific evidence for Rhodiola components having anti-disease benefits in humans. A clinical trial showed significant effect for a Rhodiola extract in doses of 340–680 mg per day in male and female patients from 18 to 70 years old with mild to moderate depression. Studies on whether Rhodiola improves physical performance have been inconclusive, with some studies showing some benefit, while others show no significant difference.

GNI’s Rhodiola rosea Extract Features and Benefits:

 Rhodiola rosea Extract  is one of GNI's most competitive products, with many advantages as list in the following, produced as our patent-pending process and know-how technology from Rhodiola rosea L. roots

•  Produced with pure water only

•  High purity: over 10% Rosavin and 3% Salidroside

•  NO solvent - residual free

•  Pesticide-free

•  Natural brown-red in appearance

•  High solubility in water

•  High anti-bacteria, and longer shelf life

Product Specifications:

1% Salidroside and 3% Rosavin HPLC,

2% Salidroside and 5% Rosavin HPLC,

1% Salidroside and 4% Rosavins HPLC,

2% Salidroside and 6% Rosavins HPLC,

3% Salidroside and 8% Rosavin HPLC,

3% Salidroside and 10% Rosavins HPLC,

50% Polyphenols UV